360° Coverage : BPA in plastic bottles impairs brain development

1 Updates
BPA in plastic bottles impairs brain development
Photo Credit: Pool, Getty Images

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new...

Filed under: news

YouTube Videos

 
 
 

1 year ago

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

The chemical can be ingested if it seeps into the contents of food and beverage containers, according to medical researchers from Duke University.

"Our study found that BPA may impair the development of the central nervous system and raises the question as to whether exposure could predispose animals and humans to neuro-developmental disorders," said Wolfgang Liedtke, associate professor of medicine, neurology and neurobiology at Duke, who led the study.

BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans, the journal Proceedings of the National Academy of Sciences reports.

Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioural issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders, according to a Duke statement.

Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the US Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.

While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.

Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the KCC2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.

MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the KCC2 gene at a higher rate, which might help to shut it down. This could trigger problems in the developing brain due to a delay in chloride removal.

"Our findings improve our understanding of how environmental exposure to BPA can affect the regulation of the KCC2 gene," Liedtke said.

IANS

Source: IANS

 

Don't miss ...

 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

blog comments powered by Disqus

Latest stories

$1bn needed to fight Ebola virus: UN
United Nations, Sep 16 (IANS) Over one billion dollars are needed to fight the West Africa Ebola outbreak - a tenfold increase in the past month, the UN's Ebola coordinator has said.
 
 
Five children die of spoiled vaccines in Syria
Damascus, Sep 16 (IANS) At least five children died after taking contaminated measles vaccines in rebel-held areas in the country's northern province of Idlib, the opposition Syrian Observatory for Human Rights said Tuesday.
 
 
'XI visit will set tone of Modi's US trip'
Washington, Sep 16 (IANS) Chinese President Xi Jinping's India visit will set the tone of Indian Prime Minister Narendra Modi's upcoming trip to the US, according to Jagat Shah, secretary general of the China-India Trade and Investment Centre.
 
 
Kenya maintains flight ban to Ebola-hit West African nations
Nairobi, Sep 16 (IANS) The Kenyan government will not lift a travel ban to West African countries affected by an outbreak of Ebola virus disease until the risk reduces to a manageable level, officials said Tuesday.
 
 
 

Latest from the Network

$1bn needed to fight Ebola virus: UN
United Nations, Sep 16 (IANS) Over one billion dollars are needed to fight the West Africa Ebola outbreak - a tenfold increase in the past month, the UN's Ebola coordinator has said. David Nabarro made the...
Read more on Business Balla
 
Modi's speech to be beamed live at iconic Times Square
New York, Sep 16 (IANS) Prime Minister Narendra Modi's address to the Indian community at a grand public reception at Madison Square Garden Sep 28 will be beamed live on giant screens at New York's iconic Times Square...
Read more on Politics Balla
 
Five children die of spoiled vaccines in Syria
Damascus, Sep 16 (IANS) At least five children died after taking contaminated measles vaccines in rebel-held areas in the country's northern province of Idlib, the opposition Syrian Observatory for Human Rights said...
Read more on Politics Balla
 
Nepal all-party conference on constitution drafting cancelled
Kathmandu, Sep 16 (IANS) A scheduled all-party conference which was expected to provide an impetus to the fragile constitution drafting process of Nepal has been cancelled due to dispute among parties about its agenda...
Read more on Politics Balla
 
'XI visit will set tone of Modi's US trip'
Washington, Sep 16 (IANS) Chinese President Xi Jinping's India visit will set the tone of Indian Prime Minister Narendra Modi's upcoming trip to the US, according to Jagat Shah, secretary general of the China-India...
Read more on Politics Balla
 
Bangladesh court to give verdict on Islamist leader's death rap appeal
Dhaka, Sep 16 (IANS) Bangladesh's apex court will Wednesday deliver the final judgment on an appeal against the verdict of the International Crimes Tribunal (ICT)-1 sentencing an Islamist party leader to death for war...
Read more on Politics Balla
 
Iraq parliament fails to endorse key ministerial nominees
Baghdad, Sep 16 (IANS) Iraqi lawmakers Tuesday failed to approve new Prime Minister Haider al-Abadi's nominees for defence, interior and tourism ministers, media reported. Jaber al-Jaberi, a Sunni nominee for defence...
Read more on Politics Balla
 
Google wants to teach programming to millions of American girls
San Francisco, Sep 16 (IANS/EFE) Internet giant Google is seeking to teach computer programming to millions of girls in the US under its Made With Code initiative, which has an eye on developing women programmers in...
Read more on Politics Balla
 
Over 260,000 internally displaced in Ukraine: UN agency
Geneva, Sep 16 (IANS) Over 260,000 people in Ukraine are internally displaced, the UN Office for the Coordination of Humanitarian Affairs (OCHA) said Tuesday. According to its latest report, OCHA said an estimated 5.1...
Read more on Politics Balla
 
Riyadh calls for 10-year fight to wipe out terror
Riyadh, Sep 16 (IANS) Saudi Arabia wants that the war on the so-called Islamic State (IS) and other terrorist organisations should continue for 10 years, Foreign Minister Prince Saud Al-Faisal has said. Addressing...
Read more on Politics Balla