360° Coverage : BPA in plastic bottles impairs brain development

1 Updates
BPA in plastic bottles impairs brain development
Photo Credit: Pool, Getty Images

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new...

Filed under: news

YouTube Videos

 
 
 

1 year ago

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

The chemical can be ingested if it seeps into the contents of food and beverage containers, according to medical researchers from Duke University.

"Our study found that BPA may impair the development of the central nervous system and raises the question as to whether exposure could predispose animals and humans to neuro-developmental disorders," said Wolfgang Liedtke, associate professor of medicine, neurology and neurobiology at Duke, who led the study.

BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans, the journal Proceedings of the National Academy of Sciences reports.

Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioural issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders, according to a Duke statement.

Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the US Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.

While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.

Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the KCC2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.

MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the KCC2 gene at a higher rate, which might help to shut it down. This could trigger problems in the developing brain due to a delay in chloride removal.

"Our findings improve our understanding of how environmental exposure to BPA can affect the regulation of the KCC2 gene," Liedtke said.

IANS

Source: IANS

 

Don't miss ...

 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

blog comments powered by Disqus

Latest stories

Indian, Asian businesses hit hard by unrest in US town
Washington, Aug 22 (IANS) Even as a semblance of order was restored in a small city in Missouri after nearly two weeks of unrest, Indian and other Asian-American-owned businesses were reported to be in a mess after days of looting.
 
 
Gambia on high alert for Ebola outbreak
Banjul, Aug 22 (IANS) Gambia's ministry of health and social welfare said Thursday that it is on high alert for a possible Ebola outbreak in the country and are taking preventive measures to tackle the disease.
 
 
Young Europeans less informed about 'legal highs': Survey
Brussels, Aug 22 (IANS) Young Europeans are less informed about "legal highs" and the effects of drugs compared to a few years ago, a survey said.
 
 
Two US Ebola patients released from hospital
Washington, Aug 22 (IANS) Two US aid workers who contracted the Ebola virus while treating patients in west Africa have been discharged from the Emory University Hospital in Atlanta, the hospital said Thursday.
 
 
 

Latest from the Network

Indian, Asian businesses hit hard by unrest in US town
Washington, Aug 22 (IANS) Even as a semblance of order was restored in a small city in Missouri after nearly two weeks of unrest, Indian and other Asian-American-owned businesses were reported to be in a mess after...
Read more on Politics Balla
 
Violence against Iraqis worst seen this century: UN
United Nations, Aug 22 (IANS) The violence against children, women and minority communities in Iraq in the past few weeks is one of the worst seen in this century, a UN spokesperson said Thursday, citing information...
Read more on Politics Balla
 
Robin Williams to be honoured at Emmys
Los Angeles, Aug 22 (IANS) Actor-filmmaker Billy Crystal will pay a tribute to late actor Robin Williams at the forthcoming Emmy Awards event. The 66-year-old comedian will lead tributes to Williams, who was found...
Read more on Celebrity Balla
 
Islamic terrorists must be defeated: US army official
Washington, Aug 22 (IANS) It is possible to contain the Islamic State (IS) forces, but not in perpetuity, a senior US army official said Thursday. Martin Dempsey, chairman of US Joint Chiefs of Staff, said during a...
Read more on Politics Balla
 
Jessica Alba's 'super' imagination
Los Angeles, Aug 22 (IANS) The "Fantastic Four" star Jessica Alba used to imagine she was "super-human". As a child, the actress used to spend hours dreaming of having special powers that would take her ahead of her...
Read more on Celebrity Balla
 
Uganda to face Niger ahead of Afcon qualifier
Kampala, Aug 22 (IANS) Head coach of Uganda Cranes Milutin 'Micho' Sredojevic said Thursday that his team will play away to Niger in an international friendly Sep 2 ahead of a 2015 Africa Cup of Nations (Afcon)...
Read more on Sport Balla
 
Serena Williams to face Townsend in US Open
Washington, Aug 22 (IANS) Defending champion Serena Williams will face compatriot Taylor Townsend in the first round of the women's singles of the US Open after the draw was concluded here Thursday. Williams, who is...
Read more on Sport Balla
 
469 children killed in Gaza: UNICEF
United Nations, Aug 22 (IANS) A senior official of the United Nations Children's Fund (UNICEF) said here Thursday that a total of 469 children were killed in the Gaza Strip, where the situation is "dire" because of its...
Read more on Politics Balla
 
Demi Lovato spends birthday at Disneyland
Demi Lovato celebrated her birthday at Disneyland. The 'Heart Attack' hitmaker sported a Darth Vader Mickey Ears helmet and a matching T-shirt as she paid a visit to the adventure park in Anaheim, California, on...
Read more on Celebrity Balla
 
Nick Cannon confirms Mariah Carey split
Nick Cannon has confirmed he and Mariah Carey have been living apart ''for a few months.'' The 'America's Got Talent' host has admitted his six-year marriage with the 44-year-old singer has been on the rocks for a while...
Read more on Celebrity Balla