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Painkiller receptor variant developed
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Painkiller receptor variant developed

Jun 17 2013, 3:28am CDT | by

Los Angeles, June 17 (IANS) Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

Los Angeles, June 17 — Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study. An...

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1 year ago

Painkiller receptor variant developed

Jun 17 2013, 3:28am CDT | by

Los Angeles, June 17 (IANS) Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

Los Angeles, June 17 — Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

An interdisciplinary group of researchers at the University of Pennsylvania has developed a variant of the mu opioid receptor that has several advantages when it comes to experimentation.

This variant can be grown in large quantities in bacteria and is also water-soluble, enabling experiments and applications that had previously been very challenging or impossible, reports Science Daily.

The study was led by Renyu Liu, assistant professor in the Department of Anaesthesiology and Critical Care at Penn's Perelman School of Medicine, and Jeffery Saven, associate professor in the Department of Chemistry in the School of Arts and Sciences.

The research was published in the Journal PLOS ONE.

The mu opioid receptor belongs to a class of cellular membrane proteins called G protein-coupled receptors, or GPCRs. Involved in wide range of biological processes, these receptors bind to molecules in the environment, initiating cellular signalling pathways.

In the case of this receptor, binding to opioid molecules leads to a profound reduction of pain but also to a variety of unpleasant and potentially fatal side-effects, a problem that researchers from multiple disciplines are attempting to address.

"There are two directions for solving this problem in basic science, either working on the opioid molecule or working on the receptor," Liu said. "We're doing the latter."

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3 weeks ago

Interim President Dr. Frank G. Pogue takes over at Cheyney University

Nov 3 2014 1:34pm CST | Source: University Business

People WatchCheyney University Dr. Frank G. Pogue, a proven leader with over 50 years of experience in higher education, is Cheyney University of Pennsylvania’s new interim president. ...
Source: University Business   Full article at: University Business
 

 
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4

5 weeks ago

Pogue named interim president of Pa. university

Oct 20 2014 2:28pm CDT | Source: University Business

People WatchThe News Star Frank G. Pogue, who retired in June as president of Grambling State University, has been named interim president of Cheyney University ...
Source: University Business   Full article at: University Business
 

 
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3

6 weeks ago

UK to lead $15M project on how patients move through health care system

Oct 9 2014 7:25am CDT | Source: Business First of Louisville

The University of Kentucky will lead a nearly $15 million research project examining how patients are cared for as they transition between hospitals, their own homes and other settings. It's a three-year national project involving experts from 14 organizations, including the University of Pennsylvania and Kaiser Permanente, according to the Lane Report. UK was chosen by the nonprofit Patient-Centered Outcomes Research ...
Source: Business First of Louisville   Full article at: Business First of Louisville
 

 
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2

7 weeks ago

Former Shaw University vice president has died

Oct 2 2014 9:16am CDT | Source: University Business

People WatchWRAL.com Jeffrey Smith, former vice president of administration and student affairs at Shaw University, has died. The news was confirmed by a spokeswoman at Cheyney University of Pennsylvania, where Smith was recently hired as vice president of student affairs a ...
Source: University Business   Full article at: University Business
 

 

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<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

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