360° Coverage : Painkiller receptor variant developed

5 Updates
Painkiller receptor variant developed
Photo Credit: Drew Hallowell, Getty Images

Painkiller receptor variant developed

Jun 17 2013, 3:28am CDT | by

Los Angeles, June 17 (IANS) Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

Los Angeles, June 17 — Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study. An...

Filed under: news

YouTube Videos

 
 
 

1 year ago

Painkiller receptor variant developed

Jun 17 2013, 3:28am CDT | by

Los Angeles, June 17 (IANS) Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

Los Angeles, June 17 — Researchers have developed a variant of a major painkiller receptor that enables scientists to perform experiments previously deemed difficult or impossible, says a study.

An interdisciplinary group of researchers at the University of Pennsylvania has developed a variant of the mu opioid receptor that has several advantages when it comes to experimentation.

This variant can be grown in large quantities in bacteria and is also water-soluble, enabling experiments and applications that had previously been very challenging or impossible, reports Science Daily.

The study was led by Renyu Liu, assistant professor in the Department of Anaesthesiology and Critical Care at Penn's Perelman School of Medicine, and Jeffery Saven, associate professor in the Department of Chemistry in the School of Arts and Sciences.

The research was published in the Journal PLOS ONE.

The mu opioid receptor belongs to a class of cellular membrane proteins called G protein-coupled receptors, or GPCRs. Involved in wide range of biological processes, these receptors bind to molecules in the environment, initiating cellular signalling pathways.

In the case of this receptor, binding to opioid molecules leads to a profound reduction of pain but also to a variety of unpleasant and potentially fatal side-effects, a problem that researchers from multiple disciplines are attempting to address.

"There are two directions for solving this problem in basic science, either working on the opioid molecule or working on the receptor," Liu said. "We're doing the latter."

IANS

Source: IANS

 
Update
5

1 week ago

Pogue named interim president of Pa. university

Oct 20 2014 2:28pm CDT | Source: University Business

People WatchThe News Star Frank G. Pogue, who retired in June as president of Grambling State University, has been named interim president of Cheyney University of Pennsylvania. ...
Source: University Business   Full article at: University Business
 

 
Update
4

3 weeks ago

UK to lead $15M project on how patients move through health care system

Oct 9 2014 7:25am CDT | Source: Business First of Louisville

The University of Kentucky will lead a nearly $15 million research project examining how patients are cared for as they transition between hospitals, their own homes and other settings. It's a three-year national project involving experts from 14 organizations, including the University of Pennsylvania and Kaiser Permanente, according to the Lane Report. UK was chosen by the nonprofit Patient-Centered Outc ...
Source: Business First of Louisville   Full article at: Business First of Louisville
 

 
Update
3

4 weeks ago

Former Shaw University vice president has died

Oct 2 2014 9:16am CDT | Source: University Business

People WatchWRAL.com Jeffrey Smith, former vice president of administration and student affairs at Shaw University, has died. The news was confirmed by a spokeswoman at Cheyney University of Pennsylvania, where Smith was recently hired as vice president of student affair ...
Source: University Business   Full article at: University Business
 

 
Update
2

7 weeks ago

And the best colleges for 2015 are...

Sep 9 2014 6:23am CDT | Source: CNBC

Research institutions fill the top 10 seats and University of Pennsylvania – Philadelphia leads the pac ...
Source: CNBC   Full article at: CNBC
 

 

Don't miss ...

 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

blog comments powered by Disqus

Latest stories

UN warns of worsening food crisis in Somalia
United Nations, Nov 1 (IANS) A UN food agency Friday warned that poor rains in Somalia may worsen the country's food crisis, a spokesperson said.
 
 
Canada suspends issuance of visas to Ebola-hit African countries
Ottawa, Nov 1 (IANS) Canada has suspended issuance of visas to residents of West African countries with "widespread and persistent-intense transmission" of Ebola virus disease, a media report said Friday.
 
 
Chinese unmanned lunar orbiter returns home
Beijing, Nov 1 (IANS) China succeeded Saturday in the world's first mission to the Moon and back, becoming the third nation to do so after the former Soviet Union and the US.
 
 
China pledges $81 mn financial assistance for Afghanistan
Beijing, Oct 31 (IANS) China Friday pledged to provide non-reimbursable assistance of 500 million yuan (about 81 million dollars) to Afghanistan this year at an international meeting on Afghanistan held here.
 
 
 

Latest from the Network

German Bundesliga standings
Berlin, Nov 1 (IANS) Following are the German Bundesliga standings after Friday's match (tabulated under matches played, won, drawn, lost, goals for, goals against, points), according to Xinhua. Bayern Munich...
Read more on Sport Balla
 
Indian appointed to UN peacekeeping panel
United Nations, Nov 1 (IANS) UN Secretary General Ban Ki-Moon has appointed Abhijit Guha, a retired Indian Army Lieutenant General, to a high-level panel to assess UN peace operations. Announcing the formation of the...
Read more on Politics Balla
 
Kim Kardashian wants to loose 10lb
Los Angeles, Nov 1 (IANS) Reality TV star Kim Kardashian, who shed weight after the birth of her daughter last year, is keen to loose 10lb (about 4.5 kg) more. She talked about loosing weight while talking to Grazia...
Read more on Celebrity Balla
 
US, EU to meet Iran over nuke talks
Washington, Nov 1 (IANS) US Secretary of State John Kerry will travel to Oman early next month for meetings with his Iranian and EU counterparts to push for a comprehensive deal over Tehran's nuclear programme by Nov...
Read more on Politics Balla
 
Amanda Bynes to remain under conservatorship
Amanda Bynes is set to remain under a conservatorship. A lawyer claiming to represent the 28-year-old actress, who was released from a psychiatric treatment facility in Pasadena, California on Thursday (10.30.14) after...
Read more on Celebrity Balla
 
Ben Affleck broke Jennifer Lopez's heart
Jennifer Lopez says Ben Affleck was the first guy who broke her heart. The 'Booty' hitmaker, who got divorced twice before she started dating the 'Gone Girl' actor in 2002, was completely devastated when they ended...
Read more on Celebrity Balla
 
Alicia Key's son is ready to be a big brother
Alicia Keys' son is ''so ready'' to be a big brother. The 33-year-old singer and husband Swizz Beatz are set to welcome their second child into the world on New Year's Eve (12.31.14) and says their four-year-old Egypt...
Read more on Celebrity Balla
 
UN warns of worsening food crisis in Somalia
United Nations, Nov 1 (IANS) A UN food agency Friday warned that poor rains in Somalia may worsen the country's food crisis, a spokesperson said. The Food and Agriculture Organisation (FAO) issued the warning that an...
Read more on Business Balla
 
1.26 mn uprooted Iraqis need shelter: UN
United Nations, Nov 1 (IANS) The UN Office for the Coordination of Humanitarian Affairs (OCHA) said that some 1.26 million internally displaced people (IDPs) throughout Iraq need shelter and basic supplies, UN...
Read more on Politics Balla
 
Price expects ghosts in new house
London, Nov 1 (IANS) Singer Katie Price feels that her new house is going to be full of ghosts. She recently moved into a west Sussex nine-bedroom mansion with husband Kieran Hayler and her five children. She's...
Read more on Celebrity Balla