360° Coverage : New TB vaccine to boost BCG efficacy

New TB vaccine to boost BCG efficacy

Washington, Oct 3 (IANS) A new vaccine may help boost the efficacy of Bacille Calmette Guerin (BCG), currently the only tuberculosis (TB) vaccine available, researchers said Wednesday.

Oct 2 2013, 7:00pm CDT | by IANS

New TB vaccine to boost BCG efficacy
Photo Credit: PHILIPPE WOJAZER, Getty Images

Washington, Oct 3 — A new vaccine may help boost the efficacy of Bacille Calmette Guerin (BCG), currently the only tuberculosis (TB) vaccine available, researchers said Wednesday.

The new vaccine, based on a genetically modified cold virus, will not replace the old vaccine, but is designed to be given following initial BCG vaccination to boost the immunity triggered by BCG, Xinhua reported citing researchers at Canada's McMaster University.

Their findings, offering new hopes for the global fight against the disease, were published in the US journal Science Translational Medicine.

BCG, typically given in the first year of life, was developed in the 1920s and has been used worldwide. It is most effective in protecting children from the disease, but doesn't work very well in adults.

The researchers began the first human clinical trial in 2009 with 24 healthy volunteers, including 12 who were previously BCG-immunised, said Professor Zhou Xing, who led the study.

"The primary goal was to look at the safety of a single dose vaccine injection as well as its potency to engage the immune system," Xing said of the phase one clinical study.

Although the researchers established that the vaccine was safe, Xing said that more clinical trials are needed to measure the vaccine's real potential.

Tuberculosis is second only to HIV/AIDS as the greatest killer worldwide due to a single infectious agent.

According to the World Health Organization, about one-third of the world's population has latent TB, which means people have been infected by TB bacteria but are not ill with disease and cannot transmit the disease. Every year, more than 8 million people are newly diagnosed with TB disease, and more than 1 million die.

IANS

Source: IANS

 
 
 

blog comments powered by Disqus

Latest stories

Facebook M is a Hybrid Personal Digital Assistant inside Messenger
Facebook M is a Hybrid Personal Digital Assistant inside Messenger
M relies on artificial intelligence and human assistance.
 
 
iPhone Users get 30 Day Free Samsung Galaxy Trial
iPhone Users get 30 Day Free Samsung Galaxy Trial
Samsung tries everything to get new customers. Now iPhone user can test a new Galaxy smartphone 30 days for free.
 
 
Microsoft released 3rd Windows 10 Updates with KB 3081438
Microsoft released 3rd Windows 10 Updates with KB 3081438
Microsoft's release schedule for Windows 10 updates is fast paced. The company released three updates within 2 weeks.
 
 
New Skinny Jeans for Women Charges and Hides iPhone
New Skinny Jeans for Women Charges and Hides iPhone
Joe's Jeans offers a Jeans for female mobile warriors. Meet the Joe's Jeans #Hello.