1 Updates
Protein links exercise to brain health: Research
Photo Credit: Mike Coppola, Getty Images

Protein links exercise to brain health: Research

Oct 12 2013, 7:18am CDT | by IANS

Washington, Oct 12 (IANS) A protein, which increases during an endurance exercise, may promote brain health, US researchers say.

Washington, Oct 12 — A protein, which increases during an endurance exercise, may promote brain health, US researchers say. Researchers from the Dana-Farber Cancer Institute and Harvard Medical...

Filed under: news

Full Story below YouTube Videos

 
 

 

26 weeks ago

Protein links exercise to brain health: Research

Oct 12 2013, 7:18am CDT | by IANS

Washington, Oct 12 (IANS) A protein, which increases during an endurance exercise, may promote brain health, US researchers say.

Washington, Oct 12 — A protein, which increases during an endurance exercise, may promote brain health, US researchers say.

Researchers from the Dana-Farber Cancer Institute and Harvard Medical School found that the FNDC5 protein, when given to non-exercising mice, turned on genes that promote brain health and encourage growth of new nerves involved in learning and memory, Xinhua reported.

The findings, reported in the Cell Metabolism journal, explain the capacity of endurance exercise to improve cognitive function, particularly in older people.

If this protein can be developed into a drug, it might lead to improved therapies for cognitive decline in older people. It can slow the toll of neuro-degenerative diseases such as Alzheimer and Parkinson, according to the researchers.

Earlier, the researchers reported that the protein is produced by muscular exertion and is released into the bloodstream as a variant called irisin.

In the new study, they found that mice voluntarily running on a wheel for 30 days will have increased metabolic activity, which spurred a rise in FNDC5 protein.

The increase of FNDC5 in turn boosted the BDNF brain-health protein in the hippocampus, the researchers said.

Hippocampus is the part of the brain involved in learning and memory.

Having shown that FNDC5 is a molecular link between exercise and increased BDNF in the brain, the scientists looked into whether artificially increasing FNDC5 in the absence of exercise would have the same effect.

So, they used a harmless virus to deliver the protein to mice, hoping the FNDC5 could reach the brain and raise BDNF activity. Seven days later, they examined the mice brains and observed a significant increase in BDNF in the hippocampus.

However, the researchers said they are not sure whether the protein that got into the brain is FNDC5 itself or irisin or perhaps another variant of the protein.

Spiegelman added that further research is needed to determine whether giving FNDC5 actually improves cognitive function in other animals.

IANS

Source: IANS

 

Don't miss ...

 

blog comments powered by Disqus

Latest stories

Legislator Wants To Stop School Choice From Creating Pseudo All-Star Teams
New Jersey’s Interdistrict Public School Choice program allows students to transfer to other, state-approved districts to get themselves, presumably, a better education, as well as take advantage of “specialized and...
 
 
United Center Leads Dual Sport Venues With Highest Average Price for Tickets To See Blackhawks and Bulls
As the NHL and NBA playoffs are getting ready to start, arenas all over North America will be preparing to host the extra games. While these venues will enjoy the extra revenue from postseason games, three venues will...
 
 
What 'Heaven Is For Real' Has In Common With Horror Movies
What 'Heaven Is For Real' Has In Common With Horror Movies
The other day, a friend of mine asked why Hollywood makes so many horror movies when most of the people he knows have no desire to see them. The answer is that there is a group of people who will go see horror movies,...
 
 
Blizzard's 'Hearthstone' Arrives On iPad Worldwide
Blizzard's 'Hearthstone' Arrives On iPad Worldwide
After a successful test in a few regions, Blizzard has now released its battle card game, Hearthstone, on Apple's  iPad worldwide. The game has made a splash on PC since an exceptionally popular closed and open beta,...
 
 
 

Latest from the Network

Legislator Wants To Stop School Choice From Creating Pseudo All-Star Teams
New Jersey’s Interdistrict Public School Choice program allows students to transfer to other, state-approved districts to get themselves, presumably, a better education, as well as take advantage of “specialized and...
Read more on Business Balla
 
United Center Leads Dual Sport Venues With Highest Average Price for Tickets To See Blackhawks and Bulls
As the NHL and NBA playoffs are getting ready to start, arenas all over North America will be preparing to host the extra games. While these venues will enjoy the extra revenue from postseason games, three venues will...
Read more on Business Balla
 
What 'Heaven Is For Real' Has In Common With Horror Movies
The other day, a friend of mine asked why Hollywood makes so many horror movies when most of the people he knows have no desire to see them. The answer is that there is a group of people who will go see horror movies,...
Read more on Business Balla
 
Blizzard's 'Hearthstone' Arrives On iPad Worldwide
After a successful test in a few regions, Blizzard has now released its battle card game, Hearthstone, on Apple's  iPad worldwide. The game has made a splash on PC since an exceptionally popular closed and open beta,...
Read more on Business Balla
 
3 Ways Microsoft Is Rethinking Its Energy Supply
I’m mostly kidding, but maybe we should go back to calling cloud services by one of its earlier names, utility computing. After all, this whole evolution is inspiring high-tech vendors from Apple to eBay to Google to...
Read more on Business Balla
 
Why CIA Director Brennan Visited Kiev: In Ukraine The Covert War Has Begun
Ukraine is on the brink of civil war, Vladimir Putin has said, and he should know because the country is already in the midst of a covert intelligence war. Over the weekend, CIA director John Brennan travelled to Kiev,...
Read more on Business Balla
 
Local Economic Forecasts From a Global/National Perspective
Small business owners attend economic forecast presentations presented by a bank or chamber of commerce. What the business owner always wants to know is what is going to happen in the local economy, but a lot of the...
Read more on Business Balla
 
The Best Cities For Raising A Family
America's Best Cities for Raising a Family Raleigh, N.C., has built a solid economy around financial services, software and energy, a major retail shipping operation and its renowned Research Triangle. The metro area...
Read more on Business Balla
 
Despite Earnings Beat American Express Shares Slide On Revenue Miss
American Express shares slid in after-hours trading Wednesday on weaker than anticipated revenue. The credit card company reported $8.2 billion in first quarter revenue, up 4% from the same period last year but short of...
Read more on Business Balla
 
Why I Don't Want To Be An Influencer
Sure it is a hot topic across the web. Expert and influencer content has determinedly become key in helping big (and small) brands in driving consumers through the buyer’s journey. From start to finish, it has been...
Read more on Business Balla
 
 
Auto Balla Sexy Balla Sport Balla TV Balla Politics Balla Movie Balla Apple Balla Business Balla Ad Balla Celebrity Balla